A high school student who was appropriately immunized
with the diphtheria–tetanus–acellular pertussis
(DTaP) series by kindergarten, but who had received
no additional boosters since, stepped on a nail while
walking barefoot. The nail was easily removed and
the lesion freely bled. What should the student be
given?
(A) Equine tetanus antitoxin
(B) Human tetanus immune globulin
(C) Prophylactic antibiotic treatment for Clostridium
tetani
(D) No treatment
(E) Tetanus toxoid
The answer is E: Tetanus toxoid. Assuming that the child
has no defi ciencies with humoral immunity, the standard
of care is to provide a booster of tetanus toxoid to
a patient with the above clinical picture. It is currently
believed that the anamnestic response (i.e., memory cell
activity) will produce ample antibody long before the
tetanus bacillus is able to produce the damaging toxin.
In other words, the patient is actively immunized.
with the diphtheria–tetanus–acellular pertussis
(DTaP) series by kindergarten, but who had received
no additional boosters since, stepped on a nail while
walking barefoot. The nail was easily removed and
the lesion freely bled. What should the student be
given?
(A) Equine tetanus antitoxin
(B) Human tetanus immune globulin
(C) Prophylactic antibiotic treatment for Clostridium
tetani
(D) No treatment
(E) Tetanus toxoid
The answer is E: Tetanus toxoid. Assuming that the child
has no defi ciencies with humoral immunity, the standard
of care is to provide a booster of tetanus toxoid to
a patient with the above clinical picture. It is currently
believed that the anamnestic response (i.e., memory cell
activity) will produce ample antibody long before the
tetanus bacillus is able to produce the damaging toxin.
In other words, the patient is actively immunized.
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