Which of the following conditions is most likely to produce a murmur in early diastole?
- Ventricular septal defect (VSD)
- Mitral stenosis
- Tricuspid regurgitation
- Aortic regurgitation
- Pulmonary stenosis
The murmurs of VSD, tricuspid regurgitation and pulmonary stenosis all occur in systole. Mitral stenosis typically produces a mid-diastolic murmur. The soft early diastolic murmur of aortic regurgitation is best heard with the patient sitting forward in held expiration, and is often described as ‘the absence of silence’ following the second heart sound. The link below provides a comprehensive guide to the evaluation of heart murmurs.
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