Question 1: Plasmin
T Is a proteolytic enzyme
T Is formed from plasminogen
T Digests fibrin
T Digests fibrinogen
Question 2: In the investigation of bleeding disorders
F The bleeding time assesses the intrinsic coagulation pathway
T The normal bleeding time is 3-10 minutes
T Blood for coagulation studies is collected into citrate solution to prevent
T The prothrombin time is prolonged in abnormalities of the extrinsic pathway
Question 3: With respect to iron metabolism
F The body contains about 40g of iron
F Most of the iron in the body is contained in ferritin
F Iron is transported in plasma as ferritin
F Haemosiderin is the main form in which iron is stored in tissues
Question 4: The following mechanisms are important in haemostasis
T Vascular spasm
T Formation of platelet plug
T Formation of blood clot
T Organisation of blood clot
Question 5: Blood coagulation
F Through the extrinsic pathway is initiated by contact of blood with a
negatively charged surface
F Through the intrinsic pathway does not occur outside the body
T Through the extrinsic pathway is initiated by tissue damage
T Through the extrinsic pathway is initiated by the release of tissue
thromboplastin
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